面白い論文/有用な論文

Single cell analysis

A Single-Cell Atlas of In Vivo Mammalian Chromatin Accessibility. Cell. 2018. PMID: 30078704
A Coupled Single-Cell CRISPR Screening and Epigenomic Profiling Reveals Causal Gene Regulatory Networks. Cell. 2019. PMID: 30580963
Multiplex single cell profiling of chromatin accessibility by combinatorial cellular indexing. Science. 2015. PMID: 25953818

ATAC-seq

An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues. Nat Methods. 2017. PMID: 28846090
The chromatin accessibility landscape of primary human cancers. Science. 2018.PMID: 30361341

Heterogeneity

The Subclonal Architecture of Metastatic Breast Cancer: Results from a Prospective Community-Based Rapid Autopsy Program "CASCADE". PLoS Med. 2016. PMID: 28027312
Multiclonal Invasion in Breast Tumors Identified by Topographic Single Cell Sequencing. Cell. 2018. PMID: 29307488
Classifying the evolutionary and ecological features of neoplasms. Nat Rev Cancer. 2017. PMID: 28912577

Breast Cancer

Research needs in breast cancer. Ann Oncol. 2017. PMID: 27831505
the St. Gallen International Expert Consensus Conference on the Primary Therapy of Early Breast Cancer 2017. Ann Oncol. 2017. PMID: 28838210
The Genomic Landscape of Endocrine-Resistant Advanced Breast Cancers. Cancer Cell. 2018. PMID: 30205045
Comprehensive molecular portraits of human breast tumours. Nature. 2012. PMID: 23000897

リンク

Xena
scholar
genome browser
oncolo
the scan

spatialtranscriptomics
trapnell-lab
nelly-lab 

NGS独学用秀逸(尾崎さん)
シカゴ頼り
干からびたウェット教授  

ASCO,ESMO,SanAntonio,StGallen,ABC,BIG,ESMO-ASIA
StGallen
2019:Estimating the magnitude of clinical benefit
2017:De-escalating and escalating treatments for early-stage breast cancer
2015:Tailoring therapies-improving the management of early breast cancer
2013:Personalizing the treatment of women with early breast cancer
2011:Strategy for subtypes-dealing with the diversity of breast cancer
2009:Thresholds for therapies

その他論文

Intratumor Heterogeneity of the Estrogen Receptor and the Long-term Risk of Fatal Breast Cancer. J Natl Cancer Inst. 2018;110:726-733. PMID: 29361175